CBD and Gut Health: How They Work Together

CBD and Gut Health: How They Work Together

Posted by Lamis Ghanayem on Jun 19th 2019

How does CBD improve gut health and promote healthy digestion? Research indicates that taking care of the gut is one of the most essential parts of achieving optimal health and wellness.

The gut is another word for your digestive system. It is responsible for absorbing nutrients from the food you eat. These nutrients support a wide range of function in the body including energy production, hormone balance, skin health, and mental health.

You may have wondered how the gut could be one the most important parts of human health and why so many people are taking probiotics. Is it just responsible for digestion, or does it do something more?

Key Facts About The Gut

Before we can understand CBD and gut health, it’s important to understand some key points:

  • immune system in your gut Around 70 percent of the immune system exists within the gut.1 By ensuring your gut is healthy, you’ll be saved from many different bodily woes because of the support your immune system receives.
  • Within the gut, there is a microbiome. Biome is a word that refers to any collection of plants or animals that exist within a specific location. The microbiome is the collection of both good and bacteria within the digestive system. It contains more than 10 trillion bacterial cells!
  • There are tight junctions within the intestines that allow for nutrients to pass through into the bloodstream and prevent harmful microbes from leaving the intestines. When the microbiome is functioning properly and is full of good healthy bacteria, it prevents harmful substances from leaking into other parts of the body and causing harm.2

CBD and Gut Health

There are many ways in which CBD shows promise in promoting gut health.

microbiome healthy bacteria

Promotes the growth of good bacteria and restrains harmful bacteria.3  These good bacteria support the gut barrier while the bad bacteria can result in leakage and a weak intestinal barrier. By having more good bacteria in your gut, the entire health of your digestive system will improve.

CBD balances the endocannabinoid system. CBD works to promote health of the endocannabinoid system. The endocannabinoid system is intertwined throughout the digestive system and the gut. It plays a role in supporting gut motility 4, aids in uptaking food, and encourages a healthy and regulated metabolism.5

One study discovered that by giving a rat a probiotic, the number of endocannabinoids in the gut rose. Endocannabinoids are cannabinoids that are produced within the body. CBD is a cannabinoid. This study lead scientists to conclude that there must be a strong link between cannabinoids and probiotics and that the action of one may play a key role in the action of the other.

CBD promotes overall digestive health. There are many different aspects of digestion that CBD can help with. One study found that CBD could promote a reduction in hyper-motility in mice.6Another found that CBD can help with many different types of gut discomfort including bloating and nausea.7

CBD strengthens gut barrier function.8 One study discovered that the body’s own endocannabinoids and phytocannabinoids like CBD show promise in not only preventing the damaging of intestinal lining, but also in repairing and promoting a healthy gut barrier. Disruption of the gut barrier has been linked to a multitude of different autoimmune and inflammatory diseases.9

How You’ll Feel When The Gut Is Healthy

cbd Healthy Gut

The gut plays a role in everything from mental health to your complexion. When you have a healthy gut, you may notice a few things:

  • You’ll be in a great mood. The gut and the brain work together in a number of different ways. They can communicate directly through the vagus nerve. This nerve runs from the gut directly to the brain. The bacteria in your gut are also responsible for producing many of the different neurotransmitters that influence mood like oxytocin, serotonin, and dopamine. With a healthy gut, you’ll be in a great mood and be able to handle all the various stressors of life.
  • Your skin will look beautiful. Over 70 years ago, scientists discovered that there was a link between the gut, the brain, and the skin.10 The gut has a major impact on hormones, and when the gut gets out of balance, hormonal levels can become imbalanced which can trigger damage to the skin. With a healthy gut, hormonal levels will be balanced, and you’ll experience beautiful glowing skin. CBD and gut health can both contribute to skin health.
  • Your sleep will improve. CBD and gut health are both known to play a role in sleep. The gut has an effect on the hormones that determine your sleep cycle? When the gut gets out of balance, it can cause your circadian rhythm to become disrupted and making sleeping difficult.11 With a health gut, you’ll sleep better, which will have a dramatic impact on all aspects of your health.
  • You’ll feel energetic and alive. Lack of energy impacts millions of people. A healthy gut and microbiome have a major impact on nutrient absorption and ensuring your blood sugar levels are optimal. By improving gut health, you can improve energy levels and overall mood.


There are many different ways that CBD can promote a healthy gut. By promoting the growth of good bacteria, balancing the endocannabinoid system, promoting overall digestive health, and strengthening gut barrier function, CBD shows tremendous promise in improving the functioning of the gut.

When you have a healthy gut, many aspects of your life will change. You will experience a better overall mood, sleep better, have healthy skin, and experience greater energy levels and vitality. CBD is a recent discovery, and with time it is possible that even more benefits and links between CBD and the gut will be discovered.

Capsules for gut health


  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515351/ ).
  2. https://www.ncbi.nlm.nih.gov/pubmed/23201091 ).
  3. http://www.jimmunol.org/content/198/1_Supplement/219.20 ).
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940133/#s002title ).
  5. https://www.ncbi.nlm.nih.gov/pubmed/21470818 ).
  6. https://www.ncbi.nlm.nih.gov/pubmed/27757083 ).
  7. https://www.ncbi.nlm.nih.gov/pubmed/27792038 ).
  8. https://www.ncbi.nlm.nih.gov/pubmed/21745190 ).
  9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266989/ ).
  10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038963/ ).
  11. https://www.ncbi.nlm.nih.gov/pubmed/22625848 ).

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